منابع مشابه
Enzymatic Formation of Catechol from Anthranilic Acid.
Anthranilic acid is known to be formed from kynurenine in animals and microorganisms (3-6) and to be degraded by cell-free extracts of a Pseudomonas species adapted to L-tryptophan (7). Catechol has been postulated as an intermediate in the catabolism of anthranilic acid on the basis of experiments utilizing sequential enzyme induction (8). Several groups of investigators have recently succeede...
متن کاملEnzvmatic Formation of Catechol from Anthranilic Acid*
Anthranilic acid is known to be formed from kynurenine in animals and microorganisms (3-6) and to be degraded by cell-free extracts of a Pseudomonas species adapted to L-tryptophan (7). Catechol has been postulated as an intermediate in the catabolism of anthranilic acid on the basis of experiments utilizing sequential enzyme induction (8). Several groups of investigators have recently succeede...
متن کاملThe concentration of anthranilic acid in saliva of orthodontic appliances.
PURPOSE Anthranilic acid is an important, the aromatic intermediate in the degradation of tryptophan in kynurenine pathway. This compound plays an important role in the regulation of immunological processes as well shows antibacterial activity. The aim of our study was to estimate the concentration of anthranilic acid in saliva of young patients with orthodontic apparatus. We also assessed corr...
متن کاملInhibition of the Na+/dicarboxylate cotransporter by anthranilic acid derivatives.
The Na(+)/dicarboxylate cotransporter NaDC1 absorbs citric acid cycle intermediates from the lumen of the small intestine and kidney proximal tubule. No effective inhibitor has been identified yet, although previous studies showed that the nonsteroidal anti-inflammatory drug, flufenamate, inhibits the human (h) NaDC1 with an IC(50) value of 2 mM. In the present study, we have tested compounds r...
متن کاملInvestigation on biological activities of anthranilic acid sulfonamide analogs
In the previous studies, the cytotoxicities of anthranilate sulfonamides were investigated. Herein, the bioactivities of 4-substituted (X = NO2, OCH3, CH3, Cl) benzenesulfonamides of anthranilic acid (5-8) are reported. The results revealed that all sulfonamides selectively exerted antifungal activity (25-50 % inhibition) against C. albicans at 4 μg/mL. Furthermore, compounds 6 and 8 show antio...
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 1910
ISSN: 0002-7863,1520-5126
DOI: 10.1021/ja01924a009